CHD2 transcriptional regulatory sub-network
The possible genes regulated by the transcription factor were obtained by calculation, and the results were displayed in the form of network
NETWORK ID: CN5922
In order to ensure the specificity of data, an ID index is built by the database itself, and each result corresponds to an ID.
CONDITION: oxetane
| ID | BRD-A69592287 |
| name | oxetane |
| type | Small molecule |
| molecular formula | C3H6O |
| molecular weight | 58.08 |
| condition dose | 10 uM |
| condition time | 6 h |
| smiles | C1COC1 |
CONDITION TYPE: trt_cp
Compound
CELL LINE: HEPG2
Cell lines used for experiments
TRANSCRIPTION FACTOR: CHD2
Transcription regulatory factors corresponding to this network
Differential expressed genes in this transcriptional regulatory sub-network
| logfc | > 0.45 and P < = 1e-5. If you want to view or download the data, you can click [expand]
| Symbol | control | control | control | condition | condition |
|---|---|---|---|---|---|
| SERPINC1 | 8.4383 | 8.8921 | 8.2767 | 5.9129 | 5.4787 |
| PSME1 | 12.7744 | 13.353 | 12.7088 | 9.4873 | 9.3415 |
| PSMD4 | 10.2844 | 10.8867 | 10.3235 | 7.7158 | 7.3941 |
| HSPD1 | 13.3921 | 13.4249 | 13.0115 | 9.3729 | 9.1862 |
| CEBPA | 10.8808 | 11.963 | 11.8004 | 5.9106 | 4.628 |
| CDK4 | 10.5887 | 10.7384 | 10.1224 | 6.4196 | 6.233 |
| TP53 | 9.382 | 9.7332 | 8.7724 | 4.8355 | 5.4626 |
| HSPA8 | 11.1003 | 10.5336 | 10.9102 | 5.0581 | 5.3116 |
| CDC42 | 8.8989 | 10.1848 | 10.5279 | 5.0793 | 5.5145 |
| CDC20 | 15 | 14.6686 | 14.7342 | 11.6514 | 11.4601 |
| PLK1 | 12.7323 | 12.5265 | 11.8648 | 4.726 | 7.1615 |
| CDKN1B | 12.4112 | 12.0797 | 11.6891 | 8.0347 | 6.6722 |
| DPH2 | 10.3061 | 10.4409 | 10.6164 | 7.021 | 7.2506 |
| SNX6 | 11.8135 | 12.2786 | 11.7951 | 7.5602 | 8.751 |
| AKT1 | 11.1846 | 12.1904 | 12.0607 | 7.5361 | 6.9665 |
| BIRC5 | 14.0623 | 15 | 14.5693 | 10.5532 | 11.3503 |
| CHERP | 10.3713 | 10.4585 | 10.0944 | 7.5361 | 7.6658 |
| TXLNA | 12.1323 | 12.8283 | 12.5843 | 8.9671 | 8.0582 |
| PNP | 12.397 | 11.6183 | 11.5246 | 7.6837 | 8.2847 |
| TM9SF2 | 9.1549 | 8.7832 | 9.0076 | 4.8355 | 4.4283 |
| LIG1 | 10.3564 | 9.8749 | 9.9745 | 4.5326 | 6.4053 |
| COASY | 6.9495 | 6.798 | 6.7347 | 3.8686 | 4.0658 |
| SLC35B1 | 12.031 | 12.2019 | 12.2576 | 7.7519 | 7.118 |
| TMEM97 | 9.7871 | 9.7614 | 9.8951 | 5.4888 | 5.8845 |
| NUP62 | 8.8398 | 8.4269 | 8.7277 | 4.4518 | 5.1961 |
| B4GAT1 | 10.9587 | 10.7531 | 10.3672 | 5.981 | 5.982 |
| ILK | 9.9081 | 9.516 | 9.3873 | 6.5091 | 6.903 |
| CIRBP | 12.0206 | 12.4863 | 11.806 | 7.7158 | 7.3283 |
| NOLC1 | 10.4084 | 9.3179 | 9.5063 | 5.1208 | 5.5698 |
| ANXA7 | 9.2818 | 9.3682 | 8.9347 | 6.141 | 4.6698 |
| LBR | 8.4659 | 8.5426 | 8.3342 | 5.3028 | 4.3476 |
| BNIP3 | 9.5303 | 9.8749 | 9.6574 | 6.2399 | 6.0691 |
| TMCO1 | 12.1944 | 12.9396 | 12.9533 | 9.0086 | 9.3028 |
| DDB2 | 9.135 | 9.1156 | 8.6863 | 3.6012 | 5.1466 |
| PGM1 | 8.6978 | 7.9942 | 7.7956 | 4.788 | 4.8227 |
| PAFAH1B3 | 11.3845 | 12.1655 | 11.6708 | 8.6201 | 8.1288 |
| PYCR1 | 12.2214 | 13.653 | 12.9215 | 8.2405 | 8.1714 |
| ACLY | 10.7165 | 10.0908 | 9.9103 | 7.0801 | 6.9738 |
| JMJD6 | 13.923 | 14.2958 | 14.5225 | 11.379 | 11.4941 |
| STUB1 | 15.0003 | 15.0002 | 15.0004 | 9.6378 | 10.2974 |
| USP7 | 9.886 | 10.1243 | 9.7194 | 6.076 | 5.8172 |
| OXA1L | 15.0002 | 15 | 14.984 | 11.5823 | 11.3187 |
| SCAND1 | 12.8389 | 13.7582 | 13.2294 | 9.4352 | 10.0908 |
| MACF1 | 11.4387 | 11.8407 | 11.0945 | 6.7745 | 6.8624 |
| WDR61 | 7.1215 | 7.8261 | 7.7046 | 4.8099 | 4.2916 |
| CNDP2 | 13.121 | 12.9735 | 12.7252 | 8.8528 | 9.649 |
| MRPS16 | 11.4595 | 11.9305 | 10.9734 | 4.726 | 6.8207 |
| ERBB2 | 11.0155 | 11.6521 | 11.1773 | 5.4036 | 6.7364 |
| PPP2R3C | 9.3278 | 9.0001 | 9.284 | 5.2952 | 6.1833 |
| RPIA | 11.8227 | 12.4653 | 11.43 | 7.9625 | 8.501 |
| ADI1 | 9.6041 | 9.3817 | 8.7574 | 5.4346 | 5.5942 |
| TSPAN4 | 11.7574 | 11.3711 | 11.5925 | 5.2467 | 6.0063 |
| VAT1 | 11.2568 | 11.5463 | 11.443 | 7.7308 | 7.2391 |
| SNRPF | 12.418 | 11.891 | 12.8072 | 9.3056 | 9.1047 |
| CAP1 | 11.4111 | 9.958 | 10.6241 | 6.484 | 6.7197 |
| PHB | 13.7256 | 15 | 15 | 9.8351 | 8.6775 |
| BZW1 | 11.4462 | 10.597 | 9.9365 | 5.981 | 6.3877 |
| PSMD8 | 11.417 | 11.8282 | 11.797 | 8.0127 | 8.9687 |
| PPP1CA | 11.7597 | 11.7381 | 11.2485 | 7.7475 | 6.644 |
| PSAP | 12.9457 | 12.0976 | 11.7616 | 5.824 | 7.0465 |
| SLC3A2 | 11.6569 | 11.1154 | 12.1137 | 7.591 | 7.4402 |
| CD59 | 9.6987 | 10.5172 | 8.9009 | 1.2766 | 2.3137 |
| SNX17 | 10.9199 | 10.268 | 10.7414 | 5.8665 | 6.1068 |
| ERP29 | 11.3871 | 11.9987 | 10.9793 | 6.6302 | 7.3529 |
| SEC11A | 9.3481 | 10.4401 | 9.7477 | 6.403 | 6.5371 |
| PSMD3 | 13.2952 | 14.2816 | 13.9311 | 9.8055 | 9.2408 |
| IGFBP4 | 7.2733 | 9.9071 | 7.2224 | 0.8214 | 0.8977 |
| SRM | 11.8626 | 11.2366 | 10.9068 | 6.9221 | 6.303 |
| LAMP1 | 10.866 | 11.9445 | 11.1975 | 5.6508 | 7.1349 |
| NME1 | 14.2425 | 14.3329 | 15 | 10.5297 | 11.0962 |
| BST2 | 7.1901 | 7.7417 | 5.4124 | 1.0055 | 0 |
| SCAMP3 | 9.8087 | 10.12 | 10.6915 | 6.614 | 6.3414 |
| DHCR7 | 11.3357 | 10.3963 | 11.395 | 6.7934 | 5.7246 |
| AFG3L2 | 9.3113 | 9.415 | 8.8367 | 4.5884 | 6.0387 |
| GMFB | 10.0629 | 9.8715 | 10.3946 | 5.6999 | 6.6184 |
| CYBA | 7.1695 | 7.8395 | 7.3015 | 3.914 | 2.6197 |
| UROS | 8.038 | 8.3466 | 8.0487 | 4.9528 | 5.0956 |
| UBE2M | 10.269 | 10.6029 | 10.5067 | 6.4217 | 7.4132 |
| RABAC1 | 10.001 | 10.5378 | 10.2071 | 5.1887 | 6.1021 |
| MED1 | 10.8083 | 11.4091 | 9.5379 | 5.0752 | 6.0964 |
| PMVK | 8.7606 | 8.4935 | 8.5153 | 6.029 | 6.2554 |
| QPRT | 8.2763 | 8.3669 | 8.559 | 5.1466 | 3.5181 |
| COCH | 7.8252 | 7.9749 | 6.9936 | 1.528 | 3.4736 |
| ACAT1 | 10.9885 | 11.2308 | 10.1138 | 6.4317 | 6.713 |
| SAC3D1 | 9.6911 | 10.0265 | 10.8094 | 6.7489 | 6.8864 |
| APMAP | 11.1673 | 12.0827 | 12.3045 | 6.0689 | 7.8706 |
| CPNE1 | 12.0457 | 12.7088 | 12.5069 | 8.0477 | 8.662 |
| KRT10 | 9.123 | 9.0596 | 8.3737 | 4.0041 | 3.4072 |
| RPL36AL | 12.1473 | 11.5323 | 11.7752 | 7.1473 | 7.6837 |
| PDIA6 | 13.1082 | 13.1504 | 13.3151 | 7.1569 | 9.2999 |
| BSCL2 | 9.4729 | 10.0875 | 9.9899 | 7.1562 | 6.6512 |
| SLC1A5 | 10.7825 | 11.1085 | 11.2877 | 8.396 | 8.5051 |
| NADK | 8.3401 | 8.5813 | 9.2516 | 5.75 | 5.4275 |
| AK2 | 11.6036 | 11.8418 | 11.6189 | 7.8117 | 7.6193 |
| SGPL1 | 9.6398 | 10.8421 | 9.7311 | 5.9671 | 6.3373 |
| PPP1R14B | 11.4019 | 12.1358 | 11.955 | 7.8855 | 8.3273 |
| NME4 | 8.966 | 10.5628 | 10.6959 | 3.9552 | 3.3854 |
| DNAJC9 | 11.5149 | 11.3921 | 11.0763 | 8.3032 | 8.7339 |
| HNRNPA1 | 13.9281 | 13.9462 | 13.0149 | 9.4653 | 10.3926 |
| GTF3A | 12.3137 | 12.7782 | 11.3247 | 8.3213 | 8.3787 |
| OAZ1 | 12.5026 | 11.5899 | 11.2249 | 7.5222 | 7.9956 |
| MTCH2 | 12.0344 | 11.7616 | 11.5418 | 6.7538 | 8.1015 |
| PRMT5 | 12.7378 | 12.5026 | 12.9123 | 8.33 | 9.0868 |
| POLDIP2 | 9.635 | 9.6049 | 9.9901 | 6.8329 | 6.8682 |
| YTHDF2 | 9.5154 | 10.4395 | 10.0475 | 5.4723 | 6.5859 |
| PTCD3 | 12.0377 | 12.5702 | 12.6918 | 9.7343 | 9.6243 |
| MRPS7 | 13.8416 | 13.9002 | 13.9482 | 10.2412 | 11.0278 |
| VKORC1 | 12.4305 | 12.0132 | 12.316 | 8.8528 | 9.5298 |
| RPS27L | 8.4408 | 8.2094 | 7.921 | 4.8727 | 3.7259 |
| MKNK2 | 11.3134 | 10.6834 | 10.0968 | 6.4762 | 6.0998 |
| HAUS4 | 8.0147 | 8.5424 | 8.7507 | 5.4641 | 5.5448 |
| SNF8 | 10.9457 | 11.3754 | 11.7245 | 5.9277 | 6.8314 |
| TRIAP1 | 11.4044 | 10.8897 | 11.1008 | 6.9576 | 7.1896 |
| AGBL5 | 9.7505 | 9.6643 | 10.0735 | 6.6606 | 6.6985 |
| SNRNP25 | 12.6249 | 12.1262 | 12.5432 | 8.6596 | 8.8074 |
| RNASEH1 | 9.2165 | 9.3117 | 9.0588 | 6.0641 | 6.454 |
| APOA2 | 11.2534 | 10.925 | 11.5108 | 7.7913 | 6.0047 |
| TSPAN14 | 12.3591 | 11.9742 | 12.1463 | 8.8576 | 8.5784 |
| GDF15 | 15 | 15 | 15 | 11.9239 | 11.2631 |
| IMP3 | 9.4038 | 9.6692 | 8.9555 | 5.9333 | 6.2643 |
| ITIH2 | 12.7945 | 11.4865 | 12.2246 | 8.572 | 8.8004 |
| DSC3 | 9.5498 | 9.8708 | 9.3901 | 6.6508 | 6.7664 |
| SAA4 | 9.0699 | 9.1939 | 8.7598 | 6.4344 | 6.3496 |
CHD2 transcriptional regulatory sub-network
The possible genes regulated by the transcription factor were obtained by calculation, and the results were displayed in the form of network
ARTICLE: CHD2
[1] CHD2-related epilepsy: novel mutations and new phenotypes.
[2] Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory.
[3] Chromatin Remodeling Proteins in Epilepsy: Lessons From CHD2-Associated Epilepsy.
[4] CHD2-Related CNS Pathologies.
[5] Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability.